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Description
In vitro experiments demonstrated that knocking out the SHP-1 gene in CD133-targeted CAR T cells significantly enhanced their cytolytic efficacy against CD133-positive glioblastoma cells

Among those tested, Cur10 demonstrated the strongest binding, exhibiting the lowest IC 50 value of 9.64 M, while Cur07 and Cur06 showed IC 50 values of 19.86 M and 20.79 M, respectively (467)

doi: 10.1016/j.jcis.2018.05.005 197 LpezVVillegasMRRodrguezVVillaverdeGLozanoDBaezaAet al

Direct force from a stream of water can damage the peptide structure

Track and follow up for adherence, AE reporting, and adjustments
