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Pre-infusion screening must therefore include a comprehensive metabolic panel, electrocardiography, and acid-base assessment

CE is an active metabolite that displays pharmacological activity, with a longer average half-life (148 15 min) than cocaine [24]

The present study does not include histological image acquisition, nor a sperm count or morphology tests that are needed to fully to define the magnitude of HnB exposure on the spermatogenesis, especially considering that sperm adverse outcomes can occur as a result of short-term exposure ( Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding authors

This has similar or better absorption to the sublingual avenue, without the risk of most of the glutathione going to the stomach and being dissolved

Innovative solutions such as prodrug strategies and targeted drug delivery systems can enhance drug stability and minimize systemic toxicity, maximizing the therapeutic potential of GST inhibitors