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Unlike native collagen, which is poorly absorbed, CPs are thought to stimulate endogenous collagen synthesis and modulate extracellular matrix metabolism, thereby improving skin hydration, elasticity, and overall appearance [6]

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Understanding NAFLD as a complex interplay between metabolism, gut microbiota and the immune response will challenge the clinical perception of NAFLD and open new therapeutic avenues

Genistein administration induced Nrf2 enhancement by activation/phosphorylation of keap1, sirt1, MAPK-ERK1/2, PKC, and estrogen receptor in other cells or tissues, such as: hippocampal tissue, hypothalamic paraventricular nucleus, ovary, and Caco-2 cells [131, 135,136,137]
