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This additional bioactive ligand, released at the site of reduction, should specifically inhibit GSH synthesis via GCL in cancer cells, but probably also in cells of the microenvironment, thereby reducing export or degradation of free oxaliplatin

The physicochemical properties of nanocarriers mainly include size and shape of nanocarriers, chemical composition (lipophilicity, biodegradability, pH), surface charge, and surface modification (Fig

Darrow K, Maison S, Liberman M (2007) Selective removal of lateral olivocochlear efferents increases vulnerability to acute acoustic injury

The results showed significant improvements in quality of life, pain, sleep quality, anxiety, depression, and general health

Gumulec, J