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Yes, and many diabetes trials added tirzepatide on top of metformin
doi: 10.3389/fphys.2020.00694 160
[DOI] [PMC free article] [PubMed] [Google Scholar] 396.Lisse T.S., Liu T., Irmler M., Beckers J., Chen H., Adams J.S., Hewison M
Similar to STZ-treated mice, training tended ( P = 0.0702) to decrease blood ketone levels, possibly due to ketone consumption as a fuel during exercise
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