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Description
While the mechanism is not fully understood, the theory involves sustained hormonal stimulation of pancreatic cells potentially triggering inflammatory cascades in susceptible individuals

Chlorogenic Acid Activates Nrf2/SKN-1 and Prolongs the Lifespan of Caenorhabditis elegans via the Akt-FOXO3/DAF16a-DDB1 Pathway and Activation of DAF16f

doi: 10.1200/jco.2017.72.7735

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The intact head was post-fixed in fresh 4% PFA at 4 C for one week
