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6.1 Other chain-breaking ATs Probucol was primarily designed and approved for medicinal use as a cholesterol-lowering agent in the treatment of coronary artery disease, and secondarily, it may provide antioxidant activity

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Supplements such as magnesium, fiber, probiotics, and senna may be particularly helpful

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This is supported by a concomitant decrease in levels of the lipid peroxidation biomarker 8-isporostane