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2.3 Disruption of airway epithelial mucosal immunity functions The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel that allows ion flux, such as chloride (Cl - ), at the apical side of airway epithelia (162164)

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downregulate fibronectin, collagen Im and Smad3

These properties include: the intranasal compound should have no unpleasant odor, should not be irritating to nasal mucosa or influence the sense of smell, and should be potent enough so that post-intranasal administration bioavailability of the drug can reach therapeutic efficacy

Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3 pathway
