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Properties of the intracellular pH-regulating systems of frog skeletal muscle

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GSH functions as an enzyme cofactor for Grxs, which are low-molecular-weight redox enzymes that are also known as thiol transferase, to maintain cellular redox homeostasis, and also acts as the primary reductant of the disulfide bonds of oxidized proteins [15] (Figure 1)

Ginsenoside Rg5 (G-Rb5) inhibited the activation of apoptotic pathway by increasing the expression of Bcl-2 and decreasing the level of Bax, and significantly reduced cisplatin-induced nephrotoxicity, oxidative stress and inflammation (Li et al., 2016

Therefore, the PD stage level analysis (based on the H&Y scale) was not considered