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Without treatment, pellagra can be fatal, which is an important factor to be considered, since its low prevalence in developed countries causes missed diagnosis and delayed treatments (, , , )

Please refer to the full prescribing information for pembrolizumab and for carboplatin or cisplatin
Therefore, no dose adjustment is required when co-administered with tirzepatide

Category 3: Bulk Drug Substances lacking sufficient documentation or evidence for the FDA to evaluate them and cannot be compounded as active ingredients
