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Zhang Y, Zhang C, Li H, Hou J (2017) Down-regulation of vascular PPAR- contributes to endothelial dysfunction in high-fat diet-induced obese mice exposed to chronic intermittent hypoxia

Although autonomic neuropathy may improve with intensive therapy and normalization of blood glucose, there is a risk to the patient, who may become hypoglycemic without being aware of it and who cannot mount a counterregulatory response

PMID: 32782236

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In a 2017 systematic review of 18 trials, including 1,143 subjects with rheumatoid arthritis, only 4 of 18 placebo-controlled trials showed a benefit of omega-3 PUFA supplementation (2.2-3.6 g/day for 12-36 weeks) on pain level reported by patients and/or assessed by physicians (158)
