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A two-hit theory explains the mechanism of NASH pathogenesis, wherein simple fat accumulation in the hepatocytes (first hit) converts to lipotoxicity (second hit) with increased levels of free fatty acids, cholesterol and other lipid metabolites (Prez-Carreras et al., 2003

Die Mitochondrien, unsere Zellkraftwerke selbst besitzen ein eigenes Glutathionsystem, das allerdings nicht ganz so ausgefeilt ist wie das System unserer Zellen

Interestingly, the mechanism involved in resensitization was different depending on whether desensitization was accompanied or not by internalization

Infusion bei Allergie Bei allergischen Beschwerden verabreichen wir Wirkstoffe, die die allergieauslsenden Botenstoffe abschwchen und den allergischen Prozess unterbrechen