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Homocysteine also increases ROS generation by phosphorylating NAPDH oxidase[115], and/or by increasing ACE activity via ACE homocysteinylation to generate angiotensin II that activates NAPDH oxidase[116]

& Kulkarni, A

The transformation of cellular phenotypes and activation of signaling pathways might participate in the pathological process [19]

doi: 10.1097/00041444-200409000-00012
