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Light, acting through melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs), plays a critical role in both circadian and sleep regulation 7,8

Individuals with glucose-6-phosphate dehydrogenase deficiency require particular care, since high-dose vitamin C given alongside glutathione has been linked to haemolytic crises in this group

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Raffi J, Suresh R, Botto N, Murase JE

Vitamin C is very prominent and the most abundant of all anti-oxidants [106]
