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Glucagon receptor agonism stimulates intestinal smooth muscle directly and triggers pro-emetic signaling in the brainstem

YuanFLiuJZhongLLiuPLiTYangKet alEnhanced therapeutic effects of hypoxia-preconditioned mesenchymal stromal cell-derived extracellular vesicles in renal ischemic injury

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In that sense, loss-of-function mutations in KEAP1 gene leading to higher NRF2 activation have been identified in several human adenocarcinoma, with lung cancer being the type where this gene is most mutated 34

Determinants of heterogeneity in ARs transcriptional output AR-binding DNA motifs Most of the reported heterogeneity has been linked to the spectrum of AREs to which AR binds and to the protein interactome that the ARE-bound AR engages, or the chromatome, to alter expression patterns of its target genes (Fig