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Liu T, Sun L, Zhang Y, Wang Y, Zheng J

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10.1179/1476830511Y.0000000028 [DOI] [PubMed] [Google Scholar] Albassam A

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Rare variants may not only cause typical familial disease but may also contribute to the burden of apparent sporadic cSVD- for example in the UK Biobank study by Cho and colleagues such rare NOTCH3 variants accounted for 0.21% of all strokes and 0.77% of all vascular dementias in the general population (362)

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Eur Heart J 39(33):30213104

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