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Description
This genetic metabolic block severely impairs the body's ability to produce cellular energy and clear out neurotoxins, directly contributing to the hallmark symptoms of ME/CFS, including profound post-exertional malaise (PEM) and unrefreshing sleep

[ 78 , 79 , 80 ] Nevertheless, additional investigation is required to comprehend the mechanisms through which BACH1 expression is induced, including low oxygen induction, oxidative stressinduced inflammatory factors, hormones and cytokines, and other potential pathways

No human clinical trials exist for BPC-157 in GERD or any other indication

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