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Brimonidine (Mirvaso), a gel that tightens blood vessels in the skin to get rid of some of your redness Calcineurin inhibitors such as pimecrolimus and tacrolimus Clindamycin (Cleocin, Clindagel, ClindaMax), an antibiotic that kills bacteria on your skin Erythromycin (Erygel), another antibiotic Ivermectin (Soolantra), which reduces inflammation Metronidazole (Flagyl) and doxycycline, also antibiotics Oxymetazoline (Rhofade), a cream Sodium sulfacetamide and sulfur (Avar, Sulfacet, Clenia, Plexion), antibiotics Oral medicines Isotretinoin (Amnesteem, Claravis, and others) is an acne drug sometimes prescribed for rosacea