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,, O 3 therapy demonstrates considerable promise as a minimally invasive modality for IVDD, particularly in addressing refractory discogenic pain through its dual mechanisms of biochemical decompression and anti-inflammatory modulation

Funding AM was funded through a talent development program at the UMCG

These associations are very real

doi: 10.3389/fnagi.2025.1667448 Received 16 July 2025 Accepted 11 September 2025 Published 01 October 2025 Volume 17 - 2025 Edited by R

It is unclear whether these contradictory findings are a consequence of analyzing the rat GPx-1 SECIS in the latter study (255) rather than the human GPx-1 SECIS region that was analyzed in the earlier study (394)