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Another study reported that GSH but not GSSG was transported by OPT6 (Pike et al., 2009)

The uptake of pravastatin on its first pass through the liver also provides a potential advantage by keeping the drug out of the systemic circulation, from which it could be taken up by muscle cells and thereby cause toxic effects such as rhabdomyolysis
Dimercaprol is toxic and may also chelate with toxic metals, which can result in their accumulation in certain organs (e.g., brain and testes) (Flora and Pachauri, 2010)

AnisiewiczAPawlikAFilip-PsurskaBTurlejEDzimiraSMilczarekMet al

The genetic modification of microorganisms effectively improves the production efficiency of ERG, allowing large-scale production under controlled fermentation conditions, which is ideal for industrial applications and can meet the demands of large-scale markets