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Description
A novel nickel complex works as a proteasomal deubiquitinase inhibitor for cancer therapy
Storage requirements vary depending on the compound
The most accurate summary is that AOD-9604 has a plausible, partly-validated lipolytic mechanism in rodents and a failed pivotal efficacy trial in humans , and both facts must be held together
For example, the interaction between components of the ESCRT complex and their precise mechanisms in lysosomal repair are largely unknown
doi: 10.1007/s11095-011-0500-z
