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This effect was ascribed to the presence of caprylic acid and capric acid in the MCT diet, which significantly elevated HB in the circulation (Lin et al., 2022)
doi: 10.1016/j.ebiom.2017.04.013 72 LinF
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2019;15(9):e1008030
Crucially, human hepatocytes exhibit 10-fold higher CPT1A sensitivity than rodent models, explaining dose-limiting hepatotoxicity (ALT elevation in 60% of non-stroke trials) [129]
