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Description
& Agid, Y

The mechanism(s) of action underlying these changes is currently unclear, but results of preclinical work supports effects of ARA 290 on insulin resistance and muscle mitochondrial biogenesis (10) as well directly on insulin release (38)

Rong, and L

However, there are mounting concerns that the assay used for LPS is not accurate at measuring LPS at lower levels seen in non-septicaemia [72]

What the dose-response data shows, how it differs from titration, and the cost and safety risks.
