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Colchicine, Neomycin, Aminosalicylic Acid, H2-blockers (e.g., Ranitidine), and Proton Pump Inhibitors (PPIs, e.g., Omeprazole): These oral medications can all interfere with the intestinal absorption of dietary B12, making the need for injectable B12 more pronounced

Equipment required for Intramuscular injections

Excitation of methyl-, ethyl-, and n-propyl cobalamin at 520 nm in the low-lying absorption band results in bond homolysis proceeding via a bound cob(III)alamin MLCT state

[2] H2 receptor antagonists (e.g., Zantac) may interfere with the absorption of food-based B12