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162,163,164 Exa-cel (Casgevy) was approved in November 2023 as the first gene-editing therapeutic drug based on the CRISPR/Cas9 system for treating sickle cell disease (SCD) and transfusion-dependent -thalassemia (TDT)

Perinatal administration of a selective serotonin reuptake inhibitor induces impairments in reproductive function and follicular dynamics in female rat offspring

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

Th1 cells and Th2 cells consume arginine for polyamine synthesis at much higher rates than Th17 cells and Treg cells, suggesting that Th17 cells and Treg cells use different substrates for polyamine synthesis from Th1 cells and Th2 cells [244]

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