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CrossRef Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53 Young Song, Woo Lee, Yong-ho Lee, Eun Kang, Bong-Soo Cha, Byung-Wan Lee International Journal of Molecular Sciences.2016
Aug 15 2011;7(4):391-6

Although hepatotoxicity is rare in the acute overdose setting, pancreatitis and hyperammonemia have been reported
Nederveen, J
These can easily add up and increase your daily calorie intake without you even noticing
