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doi: 10.1038/sj.onc.1210796 7 WangWKryczekIDostalLLinHTanLZhaoLet al

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[94] demonstrated that sodium butyrate supplementation, combined with higher concentrate intake, affected epithelial thickness in specific rumen regions and upregulated the expression of genes and proteins related to rumen barrier function, such as MCT1 and Claudin-4 [95,96]

However, the development of drug resistance remains a significant challenge