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The responsible clinical approach Put together, the defensible version of heavy metal detox looks nothing like a 7-day cleanse

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25 Furthermore, the Nrf2-Keap1 system is an evolutionarily conserved intracellular defense mechanism which plays a pivotal role in regulating antioxidant defenses

From our point of view, therapeutic options must not only be directed to reach a molecular target, which ultimately would represent a fixed picture of the disease, but also to restore physiological global context in terms of nitro-oxidative stress and inflammatory response, just as the antioxidant treatment seems to act