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& MacArthur, C
C., Xu, Z., Guley, K., Yuan, H
Front Immunol 10:969
Glutathione synthetase deficiency has been incriminated as the cause of chronic hemolytic anemia alone (due to isolated RBC enzyme deficiency) and as the cause of a generalized syndrome (due to enzyme deficiency in many tissues) characterized by mild hemolytic disease, severe metabolic acidosis, and mental deterioration
neurological In animal studies, it protected brain cells from toxic substances and from damage caused by reduced blood flow to the brain, as happens in a stroke
