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In addition, levels of Toll Like Receptor 4 (TLR4) and inflammatory factors, such as Nuclear Factor B (NF-B), IL-6 and Monocyte Chemoattractant Protein-1 (MCP-1), were also significantly decreased compared to the untreated PE group

doi: 10.2174/1874609815666220304193925 93

The clean reads were mapped to the Rattus norvegicus reference genome (Rnor_6.0) using STAR spliced read aligner 36 , and the Rsubread package in R, which contains the feature Counts function 37 , was applied to determine count matrices of gene counts

Further Information For additional detail on peptide synthesis processes, please refer to our How Peptides Are Made blog