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Safety comparisons among monoamine oxidase inhibitors against Parkinsons disease using FDA adverse event reporting system

ATF4 activation increases pro-apoptotic ER and mitophagy mediator proteins, mitochondrial fragmentation and MMP loss, and decreases cell viability under chronic ER stress As described earlier, ATF4 is a transcription factor that is activated in response to chronic ER stress in many diseases 33,34

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