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Although there are some links between TMAO and MAFLD and administration of TMAO impairs liver function and increases hepatic triglyceride accumulation and lipogenesis in animal models, whether reducing TMAO concentrations could prevent MAFLD remains unclear due to lack of relevant studies
doi: 10.5858/arpa.2019-0561-RA [DOI] [PubMed] [Google Scholar] 16.Maldonado JL, Fridlyand J, Patel H, et al
This geographic bias not only restricts our understanding of global microbial diversity but also risks misclassification and reduced diagnostic accuracy when applying these tools across diverse populations (Blake, 2024)

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