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Interestingly, cetaceans have undergone a reduction of the GST gene family, with bowhead whales ( Balaena mysticetus ) having 16 GSTs, while mice have 30 copies and Weddell seals have an intermediate number of 22 GSTs (Tian et al., 2019)
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In conclusion, ferroptosis has broad developmental prospects, and it is expected to be a new approach for treating SIC by precisely manipulating its molecular mechanism
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