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Negrao MV, Skoulidis F, Montesion M, Schulze K, Bara I, Shen V, Xu H, Hu S, Sui D, Elamin YY, Le X, Goldberg ME, Murugesan K, Wu CJ, Zhang J, Barreto DS, Robichaux JP, Reuben A, Cascone T, Gay CM, Mitchell KG, Hong L, Rinsurongkawong W, Roth JA, Swisher SG , Lee J, Tsao A, Papadimitrakopoulou V, Gibbons DL, Glisson BS, Singal G, Miller VA, Alexander B, Frampton G, Albacker LA, Shames D, Zhang J, Heymach JV

722 Another compound, 7773, specifically disrupts the IGF2BP1-Kras mRNA interaction, effectively inhibiting IGF2BP1s pro-oncogenic activity

According to the AD 2021 Facts and Figures report, a total of $355 billion is estimated to be spent in 2021 on care for older people with dementia in the US, and the COVID-19 pandemic has posed economic hardships (Alzheimers Association, 2021)

GATA1 rescue assay For rescue experiments, erythroid cells were infected with USP7 shRNA or control shRNA lentiviruses for 3 days

Fltou, M