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The extent of lipid peroxidation was expressed as MDA using a molar extinction coefficient for MDA of 1.56 105 mol/L/cm

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Beyond thyroidal hyperfunction, Graves disease may manifest with extra-thyroidal complications, most notably thyroid-associated orbitopathy, in which fibroblasts and preadipocytes in the orbit express the TSHR and insulin-like growth factor 1 receptor (IGF-1R), leading to tissue expansion, edema, and fibrosis under autoantibody stimulation [19,20]