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Wang C, Dong S, Zhang L, et al
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Amphetamine increases the concentration of dopamine in the synaptic cleft by entering the presynaptic neuron by diffusing across the neuronal membrane directly or through DAT, competitive reuptake inhibition at the transporter, and finally, the reversal of dopamine transport through DAT (i.e., dopamine efflux) [159,160,161]

When the body is injured, Thymosin Beta-4 is upregulated at the site of damage

Moreover, rather than damage to the palmar cutaneous branches of the median nerve and local free nerve endings, Vanhees et al proposed a biomechanical origin for pillar pain, citing the division of the flexor retinaculum as the primary cause

This guarantees an expected therapeutic effect without undesirable negative outcomes
