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Peroxiredoxin (Prx) 3, a cysteine-dependent peroxidase enzyme, is also present in the mitochondria, whereas Prx5 can also be found in the cytosol, in peroxisomes, and in the nucleus [28]

Deficiency can occur in certain populations, including older adults, vegans, individuals with pernicious anaemia, those with malabsorption disorders such as Crohn's disease or coeliac disease, people who have had bariatric surgery or gastrectomy, and those on long-term medication such as metformin or acid-suppressing drugs

Figure 8 Discussion A growing evidence has suggested that regulated necrosis could induce numerous inflammation and serves as a therapeutic target of AKI (Lin and Hsu, 2020)
A., Maroney, M

These are particularly relevant for athletes or those recovering from significant injuries
