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Liu J, Zhang L, Ren Y, Gao Y, Kang L, Qiao Q

Hollander, et al
Meta-analyses published between 2022 and 2024 consistently report an 1824% elevation in lung cancer incidence among smokers receiving -carotene supplements, a finding corroborated by large-scale trials such as ATBC and CARET (246)
In cisplatin only treated rats, the induced renal injury increased protein levels of the efflux transporters MRP2 and MRP4 while expression of OAT1, OAT3, OCT1 and OCT2 was reduced

A foam can also offer better penetration in certain vehicle formulations, depending on the carrier and emollients used
