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Conversion to GABA: The reaction with glutamate decarboxylase removes a carboxyl group from glutamate, converting it into GABA
doi: 10.1182/blood.V97.1.192 139 ShinDSZaretskyJMEscuin-OrdinasHGarcia-DiazAHu-LieskovanSKalbasiAet al
In a retrospective chart review of 306 pediatric patients treated with cisplatin or carboplatin between 2000 and 2012, post-chemotherapy ototoxicity was detected in 48%, and clinically significant ototoxicity was present in 30% (114)
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