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TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma

In patients with CKD, the accumulation of IS, a metabolite of tryptophan, as a result of impaired renal excretion, can result in various health-related complications (80)

This process also indirectly reflects the regulation of mitochondrial function by statins, and since mitochondrial function is closely related to inflammatory responses and the like, it can provide a basis for statins to exert anti-inflammatory and other effects (180)

DEX exhibits the induction of ferroptosis in lens epithelial cell line in vitro, in cultured rat lens ex vivo and in the anterior chamber-DEX-injected rat models in vivo

This results in an overloaded immune system and a heightened immune response