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[DOI] [PMC free article] [PubMed] [Google Scholar] [13].McNally JS, Saxena A, Cai H, Dikalov S, Harrison DG, Regulation of xanthine oxidoreductase protein expression by hydrogen peroxide and calcium

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We emphasize its combined effect on hippocampal neurons, which are known to be particularly vulnerable (Iwasaki et al., 2003), counteracting both early and delayed neural damage and achieving full functional recovery (based on the Morris water maze test, inclined beamwalking test, and lateral push test)

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Furthermore, many researchers have found that reduced GSH levels and GSH-dependent antioxidant enzyme activity in damaged myocardium due to excess ROS and disruption of the GSH synthesis process, along with increased oxidative damage and ferroptosis