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Description
AOD 9604 AOD-9604 is a synthetic peptide derived from a modified fragment of human growth hormone (HGH), specifically the C-terminal 15amino-acid region (with an additional amino acid added for stability)
It was investigated but did not become an approved obesity drug

The crude peptides were subsequently purified by reverse-phase chromatography on a C18 column with a linear gradient of water and acetonitrile containing 0.1% TFA, and their molecular masses were verified by liquid chromatographymass spectrometry (LC/MS)

Because RNA-seq showed that bladder clock genes were rhythmically expressed in ADx + vehicle mice but genes known to be involved in urinary function and fluctuate diurnally (such as Cx43 , Piezo1, and TRPV4) were not (Supplementary Fig

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