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This inhibition was concentration-dependent, with IC 50 values of 20.25 and 7.88 M, respectively as shown in Figure 2e
[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Riedijk M.A., Stoll B., Chacko S., Schierbeek H., Sunehag A.L., van Goudoever J.B., Burrin D.G

No appreciable change was observed in the kidney of GK rats

The mice were subcutaneously administered once daily for 21 days
