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Retrieved May 6, 2025, from National Institutes of Health, Office of Dietary Supplements

Efficacy and Safety of a Fixed Combination of Cinnarizine 20 mg and Dimenhydrinate 40 mg vs Betahistine Dihydrochloride 16 mg in Patients with Peripheral Vestibular Vertigo: A Prospective, Multinational, Multicenter, Double-Blind, Randomized, Non-inferiority Clinical Trial

This finding indicates the main challenges related to -PL production, i.e., low yield and low production, respectively arising due to co-products potentially generated by these biosynthetic gene clusters during fermentation (Figure 3), and unknown rate-limiting steps in the -PL biosynthetic pathway (Yamanaka et al., 2020)

A rotating selection from the Disguised Alpha catalog