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Specifically, iron overload conditions have been shown to increase the expression and activity of T-type calcium channels, leading to enhanced iron influx into the cardiomyocytes

It's important to note that free PUFAs themselves do not directly drive ferroptosis

10.1099/acmi.ac2021.po0053 [DOI] [Google Scholar] Wang CH, Hsieh YH, Powers ZM, Kao CY

Association of leg-length inequality with knee osteoarthritis: A cohort study

Inverse variance weighting (as main analysis), weighted median estimate, robust adjusted profile score, MR-Egger, and MR-PRESSO (sensitivity analyses) were performed to calculate causal estimates
