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doi: 10.1016/j.vetimm.2015.04.007 67 RntvedCMAndersenJBDernfalkJIngvartsenKL

10.3389/fped.2020.00451

In addition, it was found that in certain individuals with low serum LDL levels there was an association with the inheritance of nonsense mutations in the PCSK9 gene which result in loss of PCSK9 activity

Interestingly, the pentamer changes into the monomeric form after interacting with activated membranes through a procedure involving an intermediate CRP form known as monomeric CRP m or pentameric CRP*, a form which represents the initial stages of subunit dissociation, in which the still-pentameric protein begins expressing antigenic and functional attributes, which are characteristic of monomeric CRP [68]

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