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Diffusion tensor tractography and neuropsychological assessment in patients with vitamin B12 deficiency

With intramuscular (IM) injections the standard treatment for severe deficiency or malabsorption conditions like pernicious anaemiaserum B12 levels rise rapidly, typically reaching therapeutic ranges within 2448 hours after the first injection

Individuals with certain genetic predispositionssuch as variants in methionine synthase (MTHFR) and cobalamin metabolism pathwaysmay respond more distinctly to B vitamin protocols