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The metastasis cascade is initiated by breaking the surrounding basement membrane and invading into the extracellular matrix (ECM), the process of which is energy-intensive [53, 54]
In addition, NAC treatment effectively protected primary human [46] and mouse hepatocytes [143] but not HepG2 cells against APAP toxicity [144]
Following treatments, cells were typsinized, pelleted, lysed with RIPA buffer
[DOI] [PubMed] [Google Scholar] 326.Reid MB, Stokic DS, Koch SM, Khawli FA, Leis AA
MBOAT1 and MBOAT2 remodel PLs to protect cells from ferroptosis independent of GPX4
