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Before initiating any medication for fatigue, clinicians should also evaluate and treat contributing medical factors (thyroid levels, anaemia, uncontrolled pain, etc.), since correcting those can sometimes markedly improve fatigue without the need for drug therapy [53]

10.1093/ibd/izaa245

In humans, most studies do not show a positive effect on the weight reduction facilitated by L-carnitine

It complements, never replaces, the basics

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