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Lakshmanan R, et al
Long known as the "bonding hormone" for its role in social attachment, mother-infant bonding, and pair formation, it has attracted growing scientific attention for a parallel set of effects that are directly relevant to aging biology
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The role of oxidative stress in the COVID-19 disease may involve recognition of the viral S-protein by angiotensin converting enzyme-2 (ACE2) receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production (Kozlov et al., 2021)
